One chromosome of each pair comes from the mother and one from the father. Each pair of chromosomes has different genes. There are 46 chromosomes (in 23 pairs) in all body cells (except the sperm and egg cells). Thus chromosomes carry our genetic information. The genes are grouped together in long, thin, thread-like structures called chromosomes. There are also long stretches of DNA, the precise role of which is still a mystery. These chemical instructions tell the body what components to make, and how, when and in what quantity to make them, in order to ensure normal working of the body. The arrangement of chemicals in the DNA is different for every gene. The genes are made of DNA (deoxyribonucleic acid). Most people have two copies of every gene - in general one copy comes from the mother and the other from the father. Genes are passed from parents to children. The body's supply and use of building and maintenance materials.The timing of the milestones of growth and development.The way babies and children grow and develop, even before they are born.Genes therefore control or influence such things as: Genes contain the body's instructions for making its parts and for its day to day running. The cell then divides in two with one copy of the genes in each new cell. It does this by making an exact copy of the genes in a cell. The active genes in a cell are only those appropriate to the cell type and its functions. Not all the genes are active in any one cell at any one time, however. The genes are the same in every cell of the body. The production and output of each cell is controlled by genes. Different parts of the body have specialised cells with special tasks, for example muscle cells are different from nerve cells, heart cells are different from brain cells. Each cell is like a tiny factory which makes the materials needed for growth and maintenance of the body. This is enough to change the finely-tuned balance of the body and produce the physical and intellectual characteristics found in people with Down's syndrome. People with Down's syndrome have the same genes as anyone else they just have 1% extra. They provide the chemical information that is needed to maintain our body and keep it working well. They are inherited from our parents and are responsible for our development from fertilized egg to fully grown adult. It still makes me cringe when I hear it, however, just as I do when people use "irregardless".Genes are present in every cell of the body. Conversely, being "up for that" was an open acknowledgement of your agreement or participation it was not private, and no secrecy was implied or conveyed.īecause English is English, and slang moves into the mainstream if it gets enough attention, they now mean the same thing. "On the down low" shares some of the same connotation, where you are describing/referring to something out of the public eye, unknown to the wife/girlfriend, or otherwise a secret.īeing "down for that" implied not only that you agreed with someone, but that you would keep your involvement a secret. It meant that you were involved in something seedy, or had inside information on something. Years ago (and the number of years is unclear to me) being "down with something" had a different meaning on the street, or amongst those who were less. I thought the speaker was confused, at first, until I heard it repeated in different contexts and came to understand that "up for that" and "down for that" have approximately the same definition to most people. It shocked me the first time I heard it (sometime in 2013, if I remember correctly). It is common in chat rooms and other online social hangouts, but does not often appear in writing. Stating that you are "down for that" appears to be a relatively recent phrase coming from slang. If you are addressing someone directly who is presently seated, you could use a command: up with you! (stand up.) (In case it's not clear, "I am up to something" means "I have an ulterior motive I don't wish to reveal.") Although you could say I am up to something, you sneaky little devil, you.
Or: up with ice cream! (Yay! Ice Cream!) You would never say I am up with something. up with the king! - meaning hey, that king is pretty great. To be up with something is only used in the imperitive, eg. You could also speak of having a disease, sometimes preceded by the verb to come if the sickness hasn't yet fully taken hold. I'm down with science means "I am familiar with science" or "science is a good thing." To be down with something is a slang phrase, and not terribly common in formal speech or writing. If you are down with something it means that you have knowledge of something or are in agreement with it.
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